Various laboratory animals – mice (Mus musculus) of six strains, rabbits (Oryctolagus cuniculus), guinea pigs (Cavia porcellus), rats (Rattus norvegicus), and Mongolian gerbils (Meriones unguiculatus) were experimentally infected with larvae of small strongyles (Cyathostominae), obtained from horse faeces and cultured to the infective larval stage L3. The attempt to transfer cyathostome larvae was aimed at developing a model for the investigation of different aspects of the life cycle and biology of these nematodes in the laboratory. Some animals were immunized (hydrocortisone) for the duration of the study. The laboratory animals were orally infected with 2–10 thousand sheathed or ex-sheathed L3 larvae of mixed cyathostome species. All attempts to inoculate any animal failed? there was no larval development in the experimental rodents and it can be stated that none of the investigated animals may serve as a suitable model host for horse nematodes of the subfamily Cyathostominae.
small strongyles, cyathostomiasis, experimental models, rabbits, guinea pigs, Mongolian gerbils
Scháňková, Š., Langrová, I,. Jankovská, I., Vadlejch, J., Čadková, Z., Křivská, D. (2018): Screening of model animals for experimental infection with equine cyathostomes. Scientia Agriculturae Bohemica, 49, 17-20. DOI: 10.2478/sab-2018-03